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Our Oral Care
Our ingredients (NOT based on really old science):
Niacinamide (AKA Vitamin B3, and/or Nicotinamide): reduces inflammation, induces natural antimicrobial peptides
Supporting literature:
- Nicotinamide: An Oral Antimicrobial Agent
- Small molecules enhance the potency of natural antimicrobial peptides
- Essential background to understand some benefits of niacinamide: Oral and Blood Neutrophil Activation States during Experimental Gingivitis
- Nicotinamide enhances apoptosis of G(M)-CSF-treated neutrophils and attenuates inflammation
- Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)
- Activation of the receptor (Gpr109a) for niacin and suppression of inflammation
Hyaluranon (AKA Hyaluronic Acid, and/or HA): successfully used in perio- and gingivitis treatments
Supporting literature:
- Hyaluronic acid: Perspectives in dentistry. A systematic review
- Neutrophil elastase levels in the gingival crevicular fluid following hyaluronan gel application in the treatment of chronic periodontitis: A randomized study
- Use of Hyaluronic Acid in Periodontal Disease Treatment: A Systematic Review
Our Articles:
Current Oral Care
The problem with current oral care (mainstream oral care ingredients are based on very old science):
Glycerin is anti-inflammatory but its breakdown products are very inflammatory:
- Degradation of glycerol using hydrothermal process
- Acetaldehyde at a Low Concentration Synergistically Exacerbates Allergic Airway Inflammation as an Endocrine-Disrupting Chemical and as a Volatile Organic Compound
- A Potential Role for Acrolein in Neutrophil-Mediated Chronic Inflammation
Fluoride and Fluorosis:
- The fluoride wars rage on
- Dental Fluorosis over Time: A comparison of National Health and Nutrition Examination Survey data from 2001–2002 and 2011–2012
Microbial disruption (eg. chlorhexidine mouthwash):
- Effects of chlorhexidine gluconate oral care on hospital mortality: a hospital-wide, observational cohort study
- Effects of chlorhexidine mouthwash on the oral microbiome
- Antiseptic mouthwash, the nitrate-nitrite-nitric oxide pathway, and hospital mortality: a hypothesis generating review
- Oral Microbiome and Nitric Oxide: the Missing Link in the Management of Blood Pressure
- Over-the-counter mouthwash use and risk of pre-diabetes/diabetes
- Effects of antiseptic mouthwash on resting metabolic rate: A randomized, double-blind, crossover study
- How Periodontal Disease and Presence of Nitric Oxide Reducing Oral Bacteria Can Affect Blood Pressure
Sodium Lauryl Sulfate (SLS):
- Dual effects of sodium lauryl sulphate on human oral epithelial structure
- Desquamative effect of sodium lauryl sulfate on oral mucosa. A preliminary study.
Titanium Dioxide (TiO2):
Alcohol-Based Mouthwash:
Complete at Home Oral Kit
Contact
info@ossacare.com
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